I don't think so.
In Windows, when I watch video in my web browser or listen to music, many sound formats are present. When "normal" sound is played (f.e. stereo mp3), in a 2.1 speaker system, the audio sounds from all the speakers, because it splits the low frequency sounds and the higher freq sounds and sends the low ones to the subwoofer. In stereo sound, there is no subwoofer chanell, still has the proper bass. I only want 2 satellites and a subwofer to be heard, when any sound is present. As it is possible in a 2.1 speaker system, it is clearly obvious that stereo can be split to proper chanells in 5.1 according to the 2.1 speaker system.