Turn off UAC
The greatest annoyance in the history of Windows: User Account Control. It askes for permission before doing anything. It eventually asks you if it is allowed to make a sound. The default button is Cancel, so you can’t just press the ENTER key.
To turn it off, go to Control Panel. Under User Account and Family settings click on the “Add or remove user account”. Choose your user account. Under the user account click on the “Go to the main User Account page” link. Under “Make changes to your user account” click on the “Change security settings” link. In the “Turn on User Account Control (UAC) to make your computer more secure” click to unselect the “Use User Account Control (UAC) to help protect your computer”. Click on the Ok button. Now reboot the system.
Turn off DEP
From XP Service Pack 2, Windows uses a technology called Data Execution Prevention to prevent harmful software from running. In XP it went fine, but the security level in Vista is much higher. It suspects normal programs to be harmful (even causes some Windows screensavers to stop working). You can turn DEP off by going to Command Prompt and then typing bcdedit.exe /set {current} nx AlwaysOff. Now reboot. You can put it back on by re-typing that command, but then with AlwaysOn.